Ongoing doctoral research psychopharmacology

Ongoing doctoral research

  • Alteration of heart rate variability and cardiac electrophysiological variables in a rodent model of brain stimulation (Dr Nagendra Madan Singh, completed).
  • A randomized, double blind, sham-controlled study of transcranial direct current stimulation (tDCS) for the attenuation of motor deficits in patients with acute ischemic stroke (Ms Ekta Francina Pinto, ongoing).
  • Structure-Function relationship of Mitochondrial Complex I in brain and muscle: Role of post-translational modifications (Ms. Niya Gowthami, ongoing)
  • To identify and validate circulating biomarkers in Parkinson’s disease with cognitive impairment (Aditi Naskar, ongoing)
  • Study of Organellar Proteins and Neuronal Structure to Assess Differential Vulnerability to Parkinson’s Disease: An Investigation Using MPTP In Experimental Systems and Electron Microscopy of Human Non- MPTP Parkinsonian Skin biopsies (Bidisha Bhaduri, ongoing) 
  • A study on Age-related changes in the cyto-architecture of human striatum (Jyothi HJ, ongoing)

Ongoing Doctoral Students

Dr. Bharath’s Lab

Niya Gowthami (2018-2023)

Hi, I am Niya Gowthami from Mysore. I have successfully completed my Masters in Biochemistry from DOS in Biochemistry, University of Mysore, Manasagangotri in the year 2016. I have qualified various National entrance exams like GATE and JRF in CSIR and ICMR. My love towards protein chemistry and curiosity on complexity of brain drew me to the world of proteomics in brain. Fortunately, I am pursuing my Ph.D. titled “Structure and Function of Mitochondrial Complex I in brain and muscle: Role of post-translational modifications” under Professor M.M. Srinivas Bharath. I study how post translational modifications (Phosphorylation, Tryptophan oxidation and Cysteine oxidation) are affecting mitochondrial Complex I in brain tissues of neurodegenerative diseases (Epilepsy and traumatic brain injury) using proteomics (MS) and structural biology (MDS).

Also, I have a strong passion towards painting and sketches. I enjoy dancing, traveling, talking to new people and listening to audiobooks.

Dr.  Alladi’s Lab

Aditi Naskar 2015-2020

I am Aditi, a brain science enthusiast and a theatre-holic. I have completed my B.Sc. & M.Sc. in Zoology from Presidency College, Kolkata & University of Calcutta, respectively. Currently, I am a Ph.D. scholar looking for biomarkers in Cerebrospinal fluid of Parkinson’s disease patients with cognitive impairment. To me the most fascinating part in the field of Neuroscience is observing the morphology of the neurons under the microscope. The journey of Ph.D. is not just exploring new facets of research but also learning to handle the challenges that life throws upon us.

Apart from being a researcher I sing and play fiddle at times!

 

Bidisha Bhaduri (June 2017-2022)

Hello, I am Bidisha. I obtained M. Phil. Neurosciences from NIMHANS, Bangalore and had my Masters in Human Physiology from University of Calcutta.

I am a Ph.D. scholar in Dr. Alladi’s lab since July 2017. Apriori I did my M.Phil dissertation with her. Parkinson’s disease being the second most common neurodegenerative disorder associated with impaired movement has an intricate and puzzling effect on the neurons of a region called Substantia Nigra. I am curious about the morphology of the neurons and the functional aspect of various organelles in neurodegeneration. I am studying different mice strains using the neurotoxin MPTP to know if dissimilarities exist between different human populations.

I love crafts and dance as stress busters!

 

Jyothi HJ (2017-2022)

Hi! I’m Jyothi. I hold a Master’s degree in Medical Microbiology from KMC Manipal. A growing curiosity if prior infections could later in life cause neurodegenerative conditions led me to Neuroscience. I joined the doctorate program at NIMHANS in 2017. In my prior role as a Research fellow in the Alladi lab, I looked at the role of normal aging in bringing about changes that occur in the human nigra. For my doctoral thesis, I’m studying the effect aging has on the cytology of aging striatum in post mortem humans.

In my free time I love to read, dance, solve jigsaw puzzles and watch the sun go down!

Ahana Bhattacharya (August 2021-26)

Hi! I obtained my Masters degree in Life Sciences from Presidency University, Kolkata, followed by which I pursued MPhil in Neurosciences from NIMHANS, Bangalore. I continued in NIMHANS as a Junior Research Fellow in the Department of Neuroimaging and Interventional Radiology in the field of Molecular Imaging and Neuro-oncology. Currently, I’m pursuing Ph.D. in the Alladi Lab. She was my joint-guide for MPhil thesis on ‘age-related protein aggregation in the post-mortem brain samples (Locus coeruleus), and the gut-brain axis with normal aging’.  I’m interested in studying the age-related changes in the normal human LC and their link with neurodegenerative disorders (AD and PD).

Apart from my love for the morphology and histology of neurons, I love gardening, cooking, singing, reading and spending time with pets.