Neuro Sciences
Neurosurgery
- Evaluation of the role of endothelial nitric oxide synthase gene variants in the natural history of aneurysmal subarachnoid hemorrhage. Investigators: Dr. Indira Devi B, Dr. Nagaraja D, Dr. Rita Christopher, (Funding by ICMR, New Delhi)
- Cortical Plasticity following intercostals musculocutaneous nerve transfer: A functional magnetic reasonance imaging study. Investigators: Dr. Dhanjaya I.Bhat, Dr. B. Indira Devi, Dr.H.R.Arvinda (Funding by DST)
- Surgical trial in traumatic lntracerebral haemorrhage. Investigators: Dr.S.Sampath, Dr. Jagath lal G, Dr. K.V.L.Narasinga Rao, Dr. Dhaval Shukla, Dr. Nupur Pruthi (Funding by NHS, New Castle University)
- Chromosomal aberrations in atypical and anaplastic meningiomas: prognostic implications. Investigators: Dr. Dwarakanath Srinivas, Dr. Vani Santosh, Dr.Sampath S, (Funding by DBT)
- Atypical and anaplastic meningiomas: prognostic implications of clinicopathological features. Investigators: Dr. Dwarakanath Srinivas, Dr. Mohd. Abdul Majid, Dr. Vani Santosh, (Funding by NIMHANS)
Neuropathology
- Multi-institutional-network programme in molecular Neuro-oncology. Investigators: Dr. Vani Santosh, Dr. Yasha TC, Dr. Arivazhagan, Dr.Paritosh Pandey, Dr. Thennarasu, Dr. Rose Dawn (Funding by DBT)
- Blood safety. Investigator: Dr. Sundar Periyavan (Funding by Karnataka State AIDS Control Society)
- Blood component separation unit and optimising availability of blood use. Investigator: Dr. Sundar Periyavan (Funding by Karnataka State AIDS Control Society)
- Molecular and histological analysis of neurological disorders associated with Mitochondrial DNA mutations. Investigators: Dr. Gayathri N, Dr. AB Taly, Dr. Yasha TC, Dr. Nalini A (Funding by DBT)
- Protein Aggregate myopathies- A clinical, Pathological, immunohistochemical, molecular genetics and proteomic investigation. Investigators: Dr. Gayathri N, Dr. Nalini A (Funding by DST)
- Studies on the seasonal variation in the ultrastructure of the renal sex segment of the lizard, Mubuya carinata. Investigators: Dr. M Bhagya, University of Mysore, Dr. BKChandrasekhar Sagar (Funding by UGC)
- Genomic proteomic and transcriptomic profiling of tuberculous meningitis. Investigators: Dr.Akhilesh Pandey, Institute of Bioinformatics, Bangalore, Dr. Keshav Prasad, Institute of Bioinformatics, Bangalore, Dr.SKShankar,Dr. Anita Mahadevan(Funding by DBT)
- Toxoplasma gondii genotypes in cerebral and extracerebral toxoplasmosis.Investigators: Dr.RSJayshree, Professor, Dept. of Microbiology, KIDWAI Memorial Institute of Oncology, Bangalore, Dr. SKShankar, Dr. Anita Mahadevan (Funding by ICMR)
- Characterization of host response to C. neoformans through quantitative proteomic analysis of cryptococcal meningitis co-infected with HIV infection. Investigators: Dr. Akhilesh Pandey, Institute of Bioinformatics, Bangalore, Dr. Keshav Prasad, InstituteofBioinformatics,Bangalore, Dr.SKShankar,Dr. Anita Mahadevan (Funding by DBT)
- Host response profile of human brain proteome in toxoplasma encephalitis.Investigators: Dr. Akhilesh Pandey, Institute of Bioinformatics, Bangalore, Dr. Keshav Prasad, Institute of Bioinformatics, Bangalore, Dr. SK Shankar, Dr. Anita Mahadevan, (Funding by DBT)
- Understanding mechanism of HIV- associated opportunistic infections of the CNS. Investigators:Dr. Akhilesh Pandey, Institute of Bioinformatics, Bangalore, Dr. Keshav Prasad, Institute of Bioinformatics, Bangalore, Dr. SK Shankar, Dr. Anita Mahadevan(Funding by DBT)
- Establishment of skin punch biopsy for evaluation of peripheral neuropathies. Investigators: Dr. Anita Mahadevan, Dr. P.Satishchandra, Dr. ABTaly,Dr. SKShankar (Funding by DBT)
- Role of CNS opportunistic infections in subsequent development of HIV Encephalitis.Investigators: Dr.Carlos Pardo, John Hopkins University, USA, Dr.SKShankar, Dr.Anita Mahadevan, Dr. P Satishchandra(Funding by NIH)
- Subregional cytoarchitectural changes and cell cycle dysregulation in the hippocampus in patients with temporal lobe epilepsy. Investigators: Dr.Lily Pal, Dept. of Pathology, SGPGI, Lucknow, Dr.SK Shankar, Dr. PSatishchandra (Funding by DST)
- Development of the human auditory cortex. Investigators: Dr. Soumya Iyengar, Additional Professor and Scientist V, NBRC, Manesar, Gurgaon, Dr.SK Shankar, Dr. Anita Mahadevan
- Immunohistochemical studies of involvement of proinflammatory protein S100A9 in traumatic brain injury conditions. Investigators: (Collaboration of HBTR) Dr. SK Shankar, Dr. Anita Mahadevan, Prof. Ludmilla A. Morozova-Roche, Professor in Medical Biophysics, Sweden
- Diagnosis of Alzheimer’s disease using fluorescent probes. Investigators: Dr. T Govindaraju, Assistant Professor, Bio-organic Chemistry Laboratory, JNCASR, Bangalore, Dr.Anita Mahadevan
- In vivo protein interaction network of P.falciparum from severe cerebral malaria patients.Investigators: (Collaboration of HBTR) Dr. SK Shankar, Dr. Anita Mahadevan, Dr.Namita Surolia, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore
- Identification of Cav 1.3 splice variants in SNpc in Parkinson’s disease.Investigators: (Collaboration of HBTR) Dr. SK Shankar, Dr. Anita Mahadevan, Prof. Vijayalakshmi Ravindranath, Centre for Neuroscience, Indian Institute of Science,Bangalore
- A retrospective study to evaluate genes expressed in Notch Pathway, prognosis and treatment response in gliomas (Provided Control brain tissues only). Investigators: (Collaboration of HBTR) Dr. SK Shankar, Dr. Anita Mahadevan, Dr. Rajeswari Narayanappa, Department of Biotechnology, DSCE, Bangalore
Epidemiology
- Monitoring and evaluation of road safety–10 India project. Investigator: Dr. Gururaj G (Funding by Johns Hopkins University, USA)
- Development of population based rural stroke registry in India. Investigator: Dr. Gururaj G (Funding by ICMR, New Delhi)
- Adolescent and youth health survey at Himachal Pradesh. Investigators: Dr. G Gururaj, Dr. Pradeep BS (Funding by National Rural Health Mission – Himachal Pradesh)
- The burden attributable to headache disorders in the general population of India Phase I: A community based survey in Karnataka State. Investigators: Dr. Gururaj, Dr. Girish N, Dr. Girish B Kulkarni, Dr. Kavita R, Dr. Subbakrishna DK, (Funding by Global Campaign)
- National mental health survey, Kolar pilot study. Investigator: Dr. Gururaj G, (Funding by MH&FW)
- Analysis of highway crashes and determinants in Kolar district. Investigator: Dr. G Gururaj (Funding by Road Traffic Injury Network (RTIN)
- The Burden attributable to headache disorders in the general population of India Phase 2: Cochrane systematic reviews. Investigators: Dr. Girish N, Dr. Girish B Kulkarni, Dr. Gururaj G, Dr. Thennarasu K (Funding by Lifting the Burden)
- Developing and implementing an integrated mental health promotion services for youth through a district empowerment model in Karnataka – Youth policy 2012 initiative. Investigators: Dr. G Gururaj, Dr. Pradeep BS, Dr. Seema Mehrotra (Funding by Department of Youth Empowerment and Sports)
- Patterns and consequences of alcohol misuse in India – a 5 region study. Investigators: Dr. Vivek Benegal, Dr. Girish N, Dr. Gurruaj G, Dr. Pratima Murthy, Dr. Prabhat Chand (Funding by WHO India Country Office)
- Iodine deficiency disorders–resurvey in Kolar. Investigator: Dr. Girish N, (Funding by IDD Cell, Govt. of Karnataka)
- Household burden of severe psychiatric conditions a study from India, a developing country. Investigators: Dr. Srikala Bharath Dr. Girish N (Funding by Sanofi Venties)
- Patient satisfaction survey at NIMHANS. Investigators: Dr. Girish N, Dr. Gururaj G, Dr. Sateesh V
- Assessment of perceived needs and barriers for care among patients with Stroke and unipolar depression. Investigators: Dr. Gautham MS, Dr. Girish B Kulkarni, Dr. Santosh Loganathan, Dr. Gururaj G (Funding by NIMHANS)
- Community follow-up study of Parkinsonism patients seen at NIMHANS. Investigators: Dr. Vivek Gupta, Dr. G Gururaj, Dr. Pramod Pal, Dr. Ravi Yadav (Funding by NIMHANS Intramural Grant)
- Stigma experience and related barriers of help-seeking in psychosis, depressive disorders and alcohol use disorders: a hospital based exploratory study. Investigators: Dr. Senthil Amudhan R, Dr. Girish N, Dr. Santosh Loganathan, Dr. Arun K (Funding by NIMHANS)
- Pilot study on youth mental health behavior survey in Bangalore: Phase 1-Development of methodology and questionnaire validation. Investigators: Dr. Sunitha Singh, Dr. Gururaj G (NIMHANS Intramural funding)
- Impact of a school based health education program for epilepsy awareness among teachers and school children. Investigator: Dr. Meena KS, Dr. Vivek Gupta (Funding by NIMHANS)
Neuroanaesthesia
- Comparison between suction above cuff endotracheal tube (SACETT) and standard endotracheal tube (SETT) on the incidence of ventilator associated pneumonia in Neuro ICU. Investigators: Dr. Sriganesh K, Dr. Sritam, Dr. Ramesh VJ, Dr. Bhadrinarayan V, Dr. Veenakumari HB, Dr. Ravikumar R
- Evaluation of the effects of 1% propofol on the cortical and sub-cortical areas of the brain using functional magnetic resonance imaging technique. Investigators: Dr. Sriganesh K, Dr. Saini J, Dr. Bhat DI (Funding by NIMHANS)
- Acute kidney injury in traumatic brain injury. Investigators: Dr. Sriganesh K, Dr. GS Umamaheswara Rao
- Blood pressure – Plethysmographic time lag as a model to quantify systemic vascular resistance: Design and validation. Investigators: Dr. Ramesh VJ, Dr. M Radhakrishnan (Funding by Life Sciences Research Board, DRDO, New Delhi)
- Heart rate variability as a tool to assess autonomic nervous system in patients with neurosurgical disorders. Investigators: Dr. M Radhakrishnan, Dr. Ramesh VJ (Funding by DST)
- A Multicenter, Prospective, Observational Registry for assessment of clinical outcomes in Indian adult (≥18-40 years, ≥41-65 and >65 years) inpatients undergoing surgery ≥2 hours duration during Suprane ® Anaesthesia. Investigators: Dr. Ramesh VJ, Dr. M Radhakrishnan (Funding by Baxter India Ltd.)
- Evaluation of the incidence of coagulopathy and its effect on outcome in patients with traumatic brain injury (TBI). Investigators: Dr. Sonia Bansal, Dr. Bhadri V Narayan, Dr. Rohini Surve, Dr. B Madhusudhana Rao (Funding by ISNACC)
- Pre-Clinical and clinical imaging of microvasculature with quantitative photoacoustic microscopy. Investigators: Dr. Manojit Pramanik, EE Department, IISc Bangalore, Dr. GS Umamaheswara Rao (Funding by NIMHANS)
- Confirmation and molecular characterization of hospital- and community-acquired staphylococcus aureus (HA and CA – MRSA) by polymerase chain reaction. Investigators: Dr. HB Veenakumari, Dr. GS Umamaheswara Rao (Funding by ICMR)
NIIR
- fMRI correlates of auditory discrimination in auditory Dys-synchrony: A Voxel-based Morphometry Study. Investigators: Dr. Rose Dawn Bharath, Dr. AK Gupta, Dr. Jayaram V, Mr. Naveen (Funding by NIMHANS)
- Brain organization in normative multilingualism. Investigator: Dr. Rose Dawn Bharath (Funding by DST)
- The role of T2* perfusion in therapeutic response assessment of CNS tuberculomas. Investigators: Dr. Anatharam, Dr. Rose Dawn Bharath
- Comparison of different sequences of images for effective brain tumor detection, segmentation and volume measurement. Investigators: Dr. Chandrajit Prasad, Dr. A.K Gupta (Funding by NIMHANS)
Neurology
- Lafora body disease – Role of malin and ubiquitin protisome pathway in the pathogenesis. Investigators: Dr.Nihar Renjen Jena, Dr.PSatishchandra, Dr.Sudeendra Rao, NBRC, New Delhi (Funding by DST)
- Kerala-Einstein Study: Healthy lifestyle, vascular disease, and cognitive decline. Investigators: Dr. PS Mathuranath, Dr. Joe Verghese (Funding by National Institute of Health (NIH)
- TMS as a biomarker to differentiate cortical dementias. Investigator: Prof. Dr. SR Chandra
- Factors determining cognitive impairment in neurocysticercosis.Investigator: Dr. SRChandra
- Role of the aldosterone synthase CYP11B2 T-344C polymorphism in vascular cognitive dysfunction associated with SVD. Investigator: Prof.Dr. SR Chandra
- Genetic determinants of cognitive impairment in cerebral small vessel disease. Investigators: Dr. Chandra SR, Dr. Rita Christopher, (Funding by ICMR, New Delhi)
- Factors determining course and prognosis in tuberculous meningitis.Cognitive functions in idiopathic Parkinsonism. Investigators: Dr.Sikandar Adwani, Dr. SR Chandra
- Glucocerebrosidase mutation in Parkinson’s disease -3 years. Investigators: Dr. Pramod Kumar Pal, Dr. Ravi Yadav (Funding by DBT)
- Genetics of movement disorders: Genotype-phenotype correlates in ataxias and Huntington’s disease. Investigator: Dr.Pramod Kumar Pal (Funding by ICMR)
- Modulation of clinical features and cortical excitability following low frequency repetitive transcranial magnetic stimulation in Writer’s Cramp and Primary Writing Tremor. Investigators:Dr. Pramod Kumar Pal, Dr. Ravi Yadav (Funding by Others)
- Gray and white matter correlates of REM sleep behaviour disorder and psychosis in Parkinson’s disease.Investigator: Dr.Pramod Kumar Pal (Funding by ICMR)
- Detection of known and new genetic mutations and phenotype-genotype correlation in Wilson’s disease from south Indian cohort. Investigators: Dr. Sanjib Sinha, Dr. AB Taly (in association with IISc, Bangalore—fundingby DBT)
- Sleep architecture and disorders in patients with Juvenile Myoclonic Epilepsy (JME) syndrome: A polysomnographic (PSG) study.Investigators: Dr. Sanjib Sinha, Dr. P Satishchandra, Dr. AB Taly (Funding by DST)
- Automated portable epilepsy-EEG system with axxonet systems. Investigators: Dr. P Satishchandra, Dr. S. Sinha, in association with Axxonet technologies, Bangalore (Funding by DBT)
- Development of Intra-operative ECoG and depth recording electrodes for surgery for refractory epilepsy – part 1. Investigators: Dr. S Sinha, Dr. P Satishchandra (Funding by DEBEL/SBMT)
- Towards identification of novel genes for reflex epilepsy (hot water epilepsy) triggered by tactile and temperature stimuli.Investigators: Dr. A Anand, JNCASR, Dr. S Sinha, Dr. P Satishchandra (Funding by ICMR)
- Genetic Analysis of the Beta-glucocerebrosidase gene in South Indian patients with Parkinson’s disease.Investigators: Prof. Arun Kumar, IISc, Prof. Pramod Kumar Pal, Dr. Ravi Yadav (Funding by DBT)
- The role of metals in the etio-pathogenesis of Parkinson’s disease.Investigators:Dr. Pramod Kumar Pal, Dr. Rita Christopher, Dr. Ravi Yadav, Dr. Rose Dawn Bharath, Dr. Jitender Saini(Funding by DBT)
- Exploring subclinical cerebellar dysfunction in patients with essential tremor, primary writing tremor and Writer’s cramp by quantitative characterization of ocular movements and eye –hand coordination and advanced neuroimaging techniques.Investigators:Dr. Pramod Kumar Pal, Dr. K Thennarasu, Dr. Jitender Saini, Dr. Ravi Yadav (Funding by DBT)
- Spectrum of autoantibody expression in generalized myasthenia gravis: Clinical phenotype and immunological correlation. Investigators: Dr Madhu Nagappa, Dr. Anita Mahadevan, Dr. Shripad Patil, Dr. AB Taly (Funding by NIMHANS)