Basic Science Research

Basic Science

Biophysics
  •  Purinergic signaling in astrocytes: Implications in pathophysiology of epilepsy. Investigator: Dr. Preeti Joshi (Funding by DBT)
  •  Calcium signaling, mitochondrial and ER function in lymphoblastoid cells with different ApoE genotypes. Investigator: Dr. Preeti Joshi (Funding by DBT)
  •  Mechanisms of action of neuropathic pain targets: Electrophysiological and calcium imaging studies in spinal cord neurons. Investigators: Dr. Preeti Joshi, Yu-Wen Li, Bristol-Myers Squibb Company, Wallingford, CT, USA, Reeba Vikramadithyan, Biocon Bristol-Myers Squibb R&D Center, Syngene International Ltd., Bangalore, Sreenivasulu Naidu Pattipati, Biocon Bristol-Myers Squibb R&D Center, Syngene International Ltd., Bangalore (Funding by Bristol-Myers Squibb Company)
  •  Role of mitochondria in selective degeneration of motor neurons in amyotrophic lateral sclerosis. Investigators: Dr. Preeti Joshi, Dr. NB Joshi, Dr. A Nalini
  •  Identification of novel modulators for ionotropic glutamate receptor, iGluA2 by in-silico screening. Investigator: Dr. B Padmanabhan
  •  Analysis of dimerization of BTB-IVR domains of Keap1 and its interaction with Cul3, by molecular modeling. Investigator: Dr. B Padmanabhan
  •  Drug discovery of potent inhibitors for epigenetic marker, BRD2 bromodomains by rational structure based approach. Investigator: Dr. B Padmanabhan (Funding by DBT)
  •  Structure-function analysis of HDAC domain of human SIRT1 and discovery of pharmaceutically acceptable SIRT1 inhibitors by rational drug design approach. Investigator: Dr. B Padmanabhan (Funding by DST)
  •  Drug discovery of novel inhibitors for human Superoxide Dismutase I (hSOD1). Investigator: Dr. B Padmanabhan, Dr. Richard Strange, Liverpool University, UK.
  •  Preclinical studies on brain tumours: combination of adjuvants with different mechanisms of radiosensitization. Investigator: Dr. Vijay Kumar Kalia, Dr. Vani Santosh (Funding by DBT)
  •  P2Y receptor mediated signaling in rat hippocampus. Ms. Biji Jose (CSIR Fellow). Guide: Dr. Preeti Joshi
  •  Interaction of P2Y receptor and TRPV1 channel in dorsal root ganglion (DRG) neurons. Mr. Mahendra Singh (UGC Fellow). Guide: Dr. Preeti Joshi
  •  Involvement of astrocytes in epilepsy.Mr. Bhanu Prakash Tewari (CSIR Fellow). Guide: Dr. Preeti Joshi
  •  Neuron-astrocyte interaction in relation to excitotoxicity in spinal neurons. Ms. Siksha Sharan (DST INSPIRE Fellow). Guides: Dr. Preeti Joshi, Dr. A Nalini
  •  Role of endoplasmic reticulum and mitochondria in calcium signaling in spinal neurons. Mr. Ajay Irmale, Guide: Dr. Preeti Joshi
  •  Protein production of mouse KEAP1-DC and screening of its designed inhibitors and crystal structure analysis of hypothetical protein TM0360. Mr. Prashant Deshmukh. Guide: Dr. B
  •  Glutamatergic and purinergic signaling in spinal sensory neurons. Mr. Yuvraj Joshi. Guide: Dr. Preeti Joshi
Biostatistics
  •  Structural equations modeling approach to study latent relations among clinical, immunological & neuroimaging parameters in schizophrenia. Investigator: Dr. DK Subbakrishna (Funding by DBT)
  •  Biostatistical consultancy for conduct of fresh anthropometric survey of a representative sample of IAF Aircrew. Investigator: Dr. DK Subbakrishna (Funding by Institute of Aerospace Medicine)
  •  Migration, poverty and access to health care:
  •  Development of screening tool for Psychiatry morbidity. Investigator: Dr. Manoj Kumar Sharma, Prof. SK Chaturvedi, Dr. P Marimuthu (Funding by INHANS)
  •  Comparison of illness severity scoring systems for mortality prediction in Neuro intensive care unit. Investigator: Dr. Sonia Bansal, Dr. Mariamma Philip
  •  Generativity in cognitive networks under Cognitive Science Research Initiative (CSI). Investigators: Dr. DK Subbakrishna, Dr. Rose Dawn Bharath, Dr. B Indira Devi (Funding by DBT)
Human Genetics 
  •  Expression and regulation of p16 and Bmi1 genes in human glioma progression. Investigators: Dr. Chetan GK, Dr. Dhananjaya I Bhat (Funding by SERB, DST) 
  •  Genetic and expression studies of HLA-G and cytokines to evaluate the immune-mediated risk of schizophrenia. Investigators: Dr. Monojit Debnath, Dr. Ganesan Venkatasubramanian, (Funding by NIMHANS) 
  •  The Immuno-psychiatry in South India study (IPS)-Immunogenetic and immuno-phenotype characterization of major psychoses. Investigators:  Prof. Vir Singh Negi, JIPMER, Prof. MA Vijayalakshmi, VIT, Dr. Monojit Debnath (Funding by Indo-French Centre for the Promotion of Advanced Research)
  •  Analysis of RB1 and p53 gene products in human brain/nervous system tumors. Investigator: Dr. R. Gope
  •  Effect of growth factors and wound healing in diabetic animal model. Investigator:   Dr. R Gope

I. “Best Poster” awards given to my Ph.D. students:

  • Thomas R, Antony Herold Prabhu PD, Mathivanan J, Rohini, Sastry KVR and Gope R.  Molecular studies on the tumor suppressor gene RB1 in human acoustic tumors.  Presented at the 10th Congress of Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB), Indian Institute of Science, Bangalore, India, held on December 7 to 11, 2003, Abstract number P17-08, page 115. (BEST POSTER AWARD GIVEN TO Ms. REMY THOMAS).
  •  Thomas R, Mathivanan J, Rohini K, Antony Herold Prabhu PD, Sivakumar D, Jayakumar PN, Indira Devi B, Satish S, Sastry KVR and Gope R.  Deregulation of the tumor suppressor gene, retinoblastoma (RB1) in human vestibular schwannomas.  Presented at the “Genes, evolution and complex diseases, an international symposium on human origins and genetics”  February 17-19, 2005, held at the National Center for Biological Sciences, Bangalore 560065, India,  Abstract number 27, printed in the proceedings pages 76-77.  (BEST POSTER AWARD GIVEN TO Ms. REMY THOMAS)
  • Rohini K, Mathivanan J, Antony Herold Prabhu PD, Thomas R, Gope ML, Anandh B and Gope R. Molecular studies on the tumor suppressor gene p53 in human brain tumors.  Presented at the 74th Annual Meeting, Society of Biological Chemists (India), November 7 to 10, 2005 held at the Central Drug Research Institute, Lucknow University, Lucknow.  Abstract number P14, printed in the proceeding page 101.  (BEST POSTER AWARD GIVEN TO Ms. ROHINI KESHAVA).

II. Research publications:

  • Rajalakshmi S and Shethna YI.  The effect of amino acids on growth, sporulation and crystal formation inBacillus thuringiensis var. thuringiensis.  J Ind Inst Sci 59: 169-176, 1977. 
  • Rajalakshmi S and Shethna YI.  Effect of L-cystine on macromolecular changes during spore and parasporal crystal formation in Bacillus thuringiensis var. thuringiensis.  J Biosci 2: 311-319, 1980. 
  • Rajalakshmi S and Shethna YI.  Spore and crystal formation in Bacillus thuringiensis var. thuringiensis  during growth in cystine and cystene.  J Biosci 2:   321-328, 1980. 
  • Rajalakshmi S.  Studies on the extrachromosomal DNA of Bacillus thuringiensis var. thuringiensis. J Ind Inst Sci 62: 21-34, 1980. 
  • Gope R and Serwer P.  Bacteriophage p22 in vitro packaging monitored by   agarose gel electrophoresis: Rate of DNA entry into capsids.  J Virol 47: 96-105, 1983. 
  • Serwer P and Gope R.  Bacteriophage p22 capsids with a subgenome length packaged DNA.  J Virol 49:293-296, 1984. 
  • Dean DC,  Gope R,  Knoll BJ, Riser ME and O’Malley BW.  A Similar 5′ flanking region is required for estrogen and progesterone induction of ovalbumin gene expression. J Biol Chem 259: 9967-9970, 1984. 
  • Dean DC, Gope R  and O’Malley BW.   A steroid regulatory region is located near the 5’-end of the ovalbumin gene.  DNA 3: 77, 1984. 
  • Gope R,  Christensen MA,  Thorson A,  Lynch HT,  Smyrk T,  Hodgson C, Wildrick DM, Gope ML and Boman BM.  Increased expression of the retinoblastoma gene in human colorectal  carcinomas relative to normal colonic mucosa.  J Natl Cancer Inst 82: 310-314, 1990. 
  • Gope R,  Christensen MA,  Thorson A,  Lynch HT,  Smyrk T,  Gope ML and Boman BM.  Molecular analysis of the retinoblastoma (RB) gene in human colorectal carcinomas. In: Hereditary colorectal cancer.  J. Utsunomiya and HT Lynch, eds, Springer- Verlag, pp 489-496, 1990. ISBN: 978-4-431-68339-1 (Print) 978-4-431-68337-7 (Online) 
  • Gope ML, Gope R and  Zarucki T.  Effect of dexamethasone and cycloheximide on the expression of amplified EGF-receptor gene in human A431 carcinoma cell line.  Mol Cell Biochem 103: 149-154, 1991. 
  • Gope ML, Chun M and Gope R.  Comparative study of the expression of Rb and p53 genes in human colorectal cancers, colon carcinoma cells lines and synchronized human fibroblasts.  Mol Cell Biochem 107:55-63, 1991. 
  • Gope R,  Gope ML,  Thorson A,  Christensen MA,  Smyrk T,  Chun M,  Alvarez L,  Wildrick DM and Boman BM.  Genetic changes at the beta-2-adrenergic-receptor locus on chromosome 5 in human colorectal carcinomas.  Anticancer Res 11: 2047-2050, 1991. 
  • Gope R and Gope ML.  Abundance and state of phosphorylation of the retinoblastoma susceptibility gene product in human colon cancer.  Mol Cell Biochem 110: 123- 133, 1992. 
  • Wildrick DM, Alfaro SA, Gope R and  Boman BM.  A study of chromosome 6 allele loss in human colorectal carcinomas.  Anticancer Res 12: 1717-1720, 1992. 
  • Gope R and Gope ML.  Effect of sodium butyrate on the expression of retinoblastoma  (RB1) and p53 gene and phosphorylation of retinoblastoma protein   in  human colon tumor cell line HT29.  Cell Mol Biol 39:589-597, 1993. 
  • Gope R. The effect of epidermal growth factor and platelet-derived growth factors on wound healing process.   Indian J Med Res. 116: 201-206, 2002.      
  • Gope ML and Gope R.  Effect of sodium butyrate on methylation pattern ofretinoblastoma (RB1) gene in human colon tumor cell line HT29.  Curr. Sci 84:430-434, 2003. 
  • Mathivanan J,  Rohini K, Thomas R, Antony Herold Prabhu PD, Gope ML and Gope R.   Molecular medicine, genetic engineering and human genetic disorders.   In:  Recent advances in Genetics and Health; P. Usha Rani, A. Jothy and M. Hema Prasad (eds.) Institute of genetics and hospital for genetic diseases, Osmania University, Hyderabad, India., Printed at Murthy Graphics,  Ameerpet, Hyderabad 500 016, India; pages 223-230, 2004.   
  • Gope R. Genetic Engineering and human genetic disorders.  In: National   seminar   on biotechnology update for teachers/researchers (Sponsored by the University Grant Commission);Sabitha Doraiswamy, G Mangai Kasturi, K Prema and CB Achuthan Unni (eds.)  School of Biotechnology, Dr. G.R. Damodaran College of Science, Civil    Aerodrome Post, Avanashi Road, Coimbatore 641014, pp18-19, 2004. 
  • Thomas R,   Mathivanan J,  Rohini K,  Antony Herold Prabhu PD,  Sivakumar D,Jayakumar PN,   Indira Devi B,   Satish S, Sastry KVR and Gope R.   Deregulation of the tumor suppressor gene retinoblastoma (RB1) in human vestibular schwannomas.  In:  Genes, evolution and complex disease: an international symposium on human origins and genetics, pp 76-77, 2005. 
  • Thomas R,  Antony Herold Prabhu PD,  Mathivanan J, Rohini,  Sivakumar D,  Jayakumar PN,  Indira Devi B,  Satish S,  Sastry KVR and Gope R. Altered structure and expression of RB1 gene and increased phosphorylation of pRb in human vestibular schwannomas.  Mol Cell Biochem.  271:  113-121, 2005. 
  • Rohini K,  Mathivanan J,  Gope ML and Gope R.  The tumor suppressor genesRB1 and p53 in human cancers.  Advanced Biotech Vol III, 16-19, 2005. 
  • Antony Herold Prabhu PD, Mathivanan J,   Keshava R,  Thomas R,   Gope ML,  Doddaballapur SK,  Somanna S,  Praharaj SS,  Chandramouli BAand  Gope R.  Age dependent phosphorylation and deregulation of p53 in human vestibular schwannomas.  Mol Carcinogensis 45:  38-46, 2006. 
  • Dayalan AHPP, Keshava R, Mathivanan J, Gope ML and Gope R.  The p53 gene and human vestibular schwannomas.  Ann Neurosci 13: 77-91, 2006. 
  • Nalini A, Yamini BK, Gayatri N, Thennarasu K and R Gope.  Familial motor neuron disease (FMMND): Study of 15 families from southern India.  J Neurol Sci 250: 140-146, 2006. 
  • Dayalan AHPP, Thomas R, Mathivanan J, Rohini K, Gope ML and Gope R.  The tumor suppressor gene retinoblastoma (RB1) in human vestibular schwannomas.  Ann Neurosci 13:  113-124, 2006. 
  • Gope ML and Gope R.  Topically applied EGF and PDGFs affect positively the co-ordinate expression of EGF and PDGF receptor genes during acute cutaneous wound-healing process.  Curr Sci 92: 618-627, 2007. 
  • Rohini K,  Mathivanan J,  Antony Herold Prabhu PD,  Subbakrishna DK,  Gope ML, Chandramouli BA, Sampath S,  Anandh B and Gope R.  Loss of  heterozygosity of the p53 gene and deregulated expression of its mRNA and protein in human brain tumors.  Mol Cell Biochem  300: 101-111, 2007. 
  • Mathivanan J, Rohini K,Gope ML,  Anandh B and  Gope R.  Altered structure and deregulated expression of the tumor suppressor gene retinoblastoma (RB1) in human brain tumors. Mol  Cell  Biochem 302: 67-77, 2007. 
  • Mathivanan J, Rohini K, Gope ML and Gope R.  Possible role of the tumor suppressor gene retinoblastoma (RB1) in human brain tumor development.  Ann Neurosci  14: 72-82, 2007. 
  • Rohini K, Mathivanan J,  Gope ML and Gope R.  Functional modulation of the p53 gene and its protein in human brain tumors.  Ann Neurosci 15:  75-86, 2008. 
  • Gope ML andGope R.Tyrosine phosphorylation of EGF-R and PDGF-R proteins during acute cutaneous wound healing process in mice.  Wound repair and Regen 17: 71-79, 2009.[PMID:19152653 PubMed – indexed for MEDLINE] 
  • Mazzucco L,  Borzini P and Gope R.  Platelet-derived factors involved in tissue repair – from signal to function. Transfusion Medicine Reviews 24:  218-234, 2010.[PMID:20656189 PubMed – indexed for MEDLINE] 
  • Gope R and Gope ML.  Tyrosine phosphorylation of EGF-R and PDGF-R and its importance during the wound healing process.  J Clin Dermatol.  1: (2), 1-11, 2010. 
  • Gope ML, Mitra R and Gope R.  Molecular Genetics of human cancers: Modulation of the tumor suppressor function of RB1 gene product in human vestibular schwannomas. In: Omics: Biomedical perspectives and applications;  Debmalya Barh, Kenneth Blum & MargaretAnne Madigan (Eds), CRC press, Taylor & Francis,  Boca Raton, FL, USA, Chapter 11; pages 213-225, 2012. 
  • Mitra R,  Indira Devi B,  Gope ML,  Subbakrishna DK and Gope R.  Sodium Butyrate modulates pRb phosphorylation and induces cell death in human vestibular schwannomas in vitro.  Ind J Exp Biol, 50:  19-27, 2012.  PMID:22279936[PubMed – indexed for MEDLINE] 
  • Mitra R, Indira Devi B and  Gope R. BAY 61-3606, CDKi and Sodium Butyrate treatments alter gene expression in human vestibular schwannomas and cause cell death in vitro.  ecancer, 6: 285, 2012.  link: ecancer 2012, 6:285 DOI: 10.3332//ecancer,2012, 285. PMID:23304241[PubMed] 
  • Mitra R, Gope ML and  Gope R. Personalized genome, Current status and the future of pharmacogenomics, In:  Omics for personalized medicine; Debmalya Barh, Dipali Dhawan and Nirmal Kumar Ganguly (eds), Springer, New York, USA, Chapter 2, pp 19-37, 2013;  ISBN 978–81-322-1183-9. 
  • Mitra R, Rohini K, Mathivanan J, Vikas V, Indira Devi B, andGope R. Bay 61-3606, CDKi and sodium butyrate treatments modulate p53 protein level and its site-specific phosphorylation in human vestibular schwannomas in vitro. Journal of cancer research, Volume 2014, Article ID 249354, 9 pages,http://dx.doi.org/10.1155/2014/249354 
  • Keshava R and  Gope R.  Sodium butyrate plus EGF and PDGF-BB aids cutaneous wound healing in diabetic mice.  Advances in Biology, Volume 2015, Article ID 527231, 10 pages,http://dx.doi.org/10.1155/2015/527231 
  • Keshava R, Muniappa N, Gope R, Ananthanarayana SR.  Anti-cancer effects of Imperata cylindica leaf extract on human oral squamous cell carcinoma cell line SCC-9 in vitro.  Asia Pac J Cancer Prev, 17:  1891-1898, 2016. DOI:http://dx.doi.org/10.7314/APJCP.2016.17.4.1891 
  • Mitra R, Vikas V, Indira Devi B, Keshava R andGope R. Sodium butyrate induces p53 dependent and independent cell death in human brain tumor cells in primary culture in vitro. Ind J Exp Biol 2016 (in press)

III. Conference/ seminar / symposia/ invited lectures:

  •  Rajalakshmi Sand Shethna YI.  The effect of amino acids on growth, sporulation   and crystal formation inBacillus thuringiensis var. thuringiensis. Presented at the 18 Annual Conference of Association of Microbiologists of India, at Madurai, Abstract   No. MC 14, 1977.
  • Rajalakshmi S and Shethna YI.  Effect of amino acids on growth, sporulation     and Crystal formation in strains of Bacillus thuringiensis var. thuringiensis – Part II – Effect of cysteine and ysteine.  Presented at the Annual Meeting of Society of Biological Chemists of India, New Delhi, India.  Abstract No. 59, 1978.
  • Rajalakshmi S and Shethna YI.  A proteinaceous toxin from the vegetative cell of Bacillus thuringiensisvar. thuringiensis   Presented at the 20th Annual Conference of  Association of Microbiologists of India, at Hissar, India, 1979.
  • Rajalakshmi S and Serwer P.  Biophysics of bacteriophage p22 assembly in vitro.   Presented at the Biophysical Society (USA) Symposium at Bethesda, Maryland 20814, USA, 1982.
  • Dean DC, Gope R,   Knoll BJ, Riser ME and O’Malley BW.  A Steroid hormone

    regulatory region is located near the 5’ end of ovalbumin gene.  Presented at the 4th Annual Congress for Recombinant DNA Research, Gordon Conference, USA, Listed in  DNA 3: 77, 1984.

  • Gope R, Christensen MA, Thorson A, Lynch HT, Smyrk T, Lanspa S, Marcus J, Fitzgibbons R, Hodgson C,  Wildrick DM and Boman BM.  Increased expression of retinoblastoma (Rb) gene in human colorectal carcinoma. Presented at the 80th Annual Meeting of the American Association for Cancer Research. May 24-27 at San Francisco, California, USA. Abstract No. 1755, Published in AACR Proceeding Vol 30: 442, 1989.
  • Gope R,   Christensen MA, Thorson A, Lynch HT,  Smyrk T,  Gope ML and 

    Boman BM. Increased expression of the retinoblastoma (Rb) gene in human colorectal carcinomas compared to normal colonic mucosa.  Presented at the 4th International  symposium on Colorectal Cancer, Kobe, Japan, November 9-11, 1989.

  • Gope R,  Chun MA, Boman BM and  Gope ML.  Growth regulated retinoblastoma and p53 gene expression in cultured human fibroblasts and primary colorectal cancers.  Presented at the Proceedings of AACR Special Conference in Cancer Research on Steroid receptors, Transcription factors and gene expression, at San Diego, California, USA, Abstract No. A32, February 10-13, 1990.
  • Gope R,  Christensen MA,  Thorson A,  Smyrk T,  Lynch HT,  Boman BM and  Gope ML.  Loss of heterozygosity at the colony-stimulating factor-1-receptor locus on chromosome 5 in human colorectal cancers.  Presented at the AACR Conference, Washington D.C., USA, May 23-26, Abstract No. 1947, published in AACR Proceedings, Vol 31: 312, 1990.
  • Gope R  and  Gope ML.  Effect of sodium butyrate on the methylation pattern and Expression of retinoblastoma (Rb) and p53 genes in human colon tumor cell line HT29.  Presented at the “Human Genome II” Conference, San Diego, California, USA, Abstract No. 55, October 21-24, 1990.
  • Gope R.  Effect of the growth factors EGF and PDGF on the induction of their corresponding receptor mRNAs during acute cutaneous wound healing process in mice.  Presented at the Euresco conference entitled “Cellular and Molecular Basis of Regeneration” held from 31 August to 5 September, 2002, in Castelvecchio Pascoli, Italy. Abstract, page 78.
  • Antony Herold Prabhu PD,  Thomas R,   Sampath S,  Indira Devi B,  Praharaj SS,  Chandra Mouli BA, Sastry KVR and Gope R.  Genetic changes at the p53 gene locus in human acoustic tumors.  Presented at the XXVI All India Cell Biology Conference & Symposium held at Advanced Center for Treatment, Research, Education in Cancer (ACTREC), Kharghar Node, Navi Mumbai, India, December 12-14, 2002; Abstract number 012, page 60.
  • Gope R.  Gave an Invited lecture on 22 February, 2003, entitled “Tumor suppressor genes”,  at Molgenix-2003 Symposium organized by  Symbiotech, CMR Institute of Management Studies, Bangalore, India.
  • Antony Herold Prabhu PD, Thomas R, Rohini, Mathivanan J, Chandramouli BA and Gope R.  Molecular analysis of the tumor suppressor gene p53 in human acoustic tumors.  Presented at the 10th Congress of Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB), Indian Institute of Science, Bangalore, India, December 7-11, 2003.  Abstract number P17-07, page 115.
  • Thomas R, Antony Herold Prabhu PD,  Mathivanan J, Rohini, Sastry  KVR and Gope R.  Molecular studies on the tumor suppressor gene RB1 in human acoustic tumors.Presented at the 10th Congress of Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB), Indian Institute of Science, Bangalore, India, December 7-11, 2003.  Abstract number P17-08, page 115.  (BEST POSTER AWARD GIVEN TO Ms. REMY THOMAS).
  • Antony Herold Prabhu PD, Rohini, Thomas R, Mathivanan J, Chandramouli BA, and Gope R.  Molecular studies on the p53 gene locus in Human acoustic tumors. Presented at the XXVII All India Cell Biology Conference & Symposium, Frontiers in Biomedical Research & Technology, January 7-10, 2004, University of Pune, Pune, India. Abstract number 01, page 33.
  • Gope R.  Gave an invited lecture entitled “Genetic Engineering and human genetic disorders” in the National seminar on biotechnology update for teachers/ researchers, sponsored by the University Grant Commission,  in the School of Biotechnology, July 7 to 9, 2004,  Dr. G.R. Damodaran College of Science, Civil  Aerodrome Post, Avanashi Road, Coimbatore 641014, India.
  • Thomas R,  Mathivanan J,  Rohini K,  Antony Herold Prabhu PD, Sivakumar D,  Jayakumar PN,  Indra Devi B,  Satish S,  Sastry KVR and Gope R.  Deregulation of the tumor suppressor gene, retinoblastoma (RB1) in human vestibular schwannomas.  Presented at the “Genes, evolution and complex diseases, an international symposium on human origins and genetics” February 17-19, 2005, held at the National Center for Biological Sciences, Bangalore 560065, India. Abstract number 2, printed in the proceedings pages 76-77. (BEST POSTER AWARD GIVEN TO Ms. REMY THOMAS)
  • Antony Herold Prabhu PD,  Mathivanan J,  Rohini K,  Thomas R,  Chandramouli BA,  Gope ML andGope R.  Structure and expression of p53 gene and altered phosphorylation of p53 protein in human vestibular schwannomas,  Presented at the “30th FEBS Congress and 9th IUBMB Conference, “The Protein World” July 2 – 7, 2005 held at Budapest, Hungary.  Abstract number N3-036P, printed in the proceedings pages 34.
  • Rohini K,  Mathivanan J,  Antony Herold Prabhu PD,  Thomas R,  Gope ML,  Anandh B and Gope R. Molecular studies on the tumor suppressor gene p53 in human brain tumors.  Presented at the 74th Annual Meeting, Society of Biological Chemists (India), November 7 to 10, 2005, held at Central Drug Research Institute, Lucknow University, Lucknow.  Abstract number P14, printed in the proceeding page 101.  (BEST POSTER AWARD GIVEN TO Ms. ROHINI  KESHAVA).
  • Mathivanan J,  Rohini K,  Antony Herold Prabhu PD, Thomas R,  Gope ML, Anandh B and Gope R. “Molecular analysis of the tumor suppressor gene retinoblastoma (RB1) in human brain tumors”, Presented at the 74th Annual Meeting, Society of Biological Chemists (India), November 7 to 10, 2005 held at Central Drug Research Institute, Lucknow University, Lucknow.  Abstract number P15, printed in the proceeding page 101.
  • Gope R.  Gave an invited lecture on the 14 November, 2005, entitled “Molecular genetics and human cancer” in the two day symposium , “Bioclinico 2005, Challenges in Medicine & Frontiers in Biosciences” organized by the Department of Biotechnology and Biochemitry at Sitadevi Ratanchand Nahar Adarsh College, #75, 5th Main, Near T.R. Mills, Chamarajpet, Bangalore 560 018.
  • Mathivanan J,  Rohini K,  Antony Herold Prabhu PD,  Thomas R,  Gope ML,  Anandh B and  Gope R. Alteration of retinoblastoma (RB1) gene in human brain tumors.  Presented at the XXIX All India Cell Biology Conference & Symposium on Gene to Genome:  Environment & Chemical Interaction (Platinum Jubilee Celebration, NASI, Allahabad);  January 17 to 20, 2006, Industrial Toxicology Research Center, PO Box 80, M.G. Marg,  Lucknow 226 001, India. Abstract number OP-24, printed in the proceeding page 184.
  • Rohini K,  Mathivanan J, Antony Herold Prabhu PD, Thomas R, Gope ML, Anandh B and Gope R. Deregulation of the tumor suppressor gene p53 in human brain tumors.  Presented at the XXIX All India Cell Biology Conference & Symposium on Gene to Genome:  Environment &  Chemical Interaction (Platinum Jubilee Celebration, NASI, Allahabad);  January 17 to 20, 2006, Industrial Toxicology Research Center, PO Box 80, M.G. Marg,  Lucknow 226 001, India.  Abstract number PP-108, printed in the proceeding page 189.
  • Gope R. Gave an invited lecture on 11 February, 2006 entitled “Tumor suppressor genes and human nervous system tumors” in the two day symposium, “Trends and Technologies in the Biochemical Sciences” in Kuvempu University organized by Department of Studies in Biochemistry & Food Technology, Post-graduate Center, Shivagangotri, Tholahunase, Davangere-577 002, Karnataka.
  • Thomas R and Gope R.  Presented a paper entitled “Molecular analysis of the expression of the tumor suppressor gene (RB1) in human vestibular tumors”  in  the, “ Proceedings of state level seminar on Vision and Trends of Biotechnology”  organized by Post graduate department of Biotechnology &  Zoology , Kuriakose Elias College (Affiliated to MG University), Mannanam,  Kottayam, Kerala; UGC Sponsored Symposium held on date 8th to 10th November,  2006, Abstract printed  in the  symposium proceeding on page 35 to 37.
  • Rohini K,  Mathivanan J,  Anandh B, Gope ML and Gope R.  Presented a paper entitled “Altered expression and phosphorylation of p53 gene product in human brain tumors”, at the XXXI All India Cell Biology Conference and Symposium on Stem Cells: Application and Prospect.  The Conference was sponsored by Indian Society of Cell Biology and Center of Advanced Study, Department of Zoology, Banaras Hindu University, Varanasi 221 005.  The conference was held in Banaras Hindu University, Varanasi, Uttar Pradesh, on 14th  to 16th  December, 2007; Abstract number Oral – 8, printed in the conference proceeding on page 37.
  • Gope R. Presented an invited lecture entitled, “The p53 gene in human brain tumors”, in Bangalore University on the 11 March, 2008.
  • Gope R.  Presented an invited guest lecture on the 1 August, 2008,  entitled “Post translational modification and human cancer” at the inauguration of the Helix Association, in Department of Biochemistry, Dr. G.R. Damodaran College of Science, Autonomous, affiliated to Bharathiar University and recongised by UGC, Civil Aerodrome Post, Avanashi Road, Coimbatore 641014, Tamil Nadu.
  • Gope R.  Presented an invited talk entitled on “Genes and cancers”  at the National Seminar on Genes and Dreams organized by Yashwant Advanced Research Center for Bioinformatics and Biotechnology and Yashwant College of Information Technology Parbhani, Maharashtra, on 11 and 12 October, 2008. Abstract number MB1, printed in the abstract book page 19.
  • Gope R.  Presented an invited talk on 20 February, 2009, entitled, “Enzyme prodrug strategies for cancer therapy” at the two day national seminar on “Enzyme Technology” organized by Dr. GR Damodaran College of Science, Coimbatore on 19-20 February, 2009.  Abstract printed in the abstract book page 29-30.
  • Mitra R,  Indira Devi B,  Gope ML and Gope R.  Presented a paper entitled “Modulation of pRb phosphorylation with sodium butyrate treatment in human vestibular schwannomas.” At the XXXIII All India Cell Biology Conference 2009 & International workshop on cell cycle regulation, held at the School of Life Sciences, University of Hyderabad, December 10-13, 2009; Abstract number AICBCP81, printed in the abstract book page 137.
  • Mitra R, Indira Devi B,  Shukla D,  Dwarakanath S,  Bhat DI,  Sampath S and Gope R.  Presented a paper entitled “Modulation of pRb status by kinase inhibitor in human vestibular schwannomas” at the 79th Annual meeting of the Society of Biological Chemists (India) – Regulation of biochemical and cellular processes in diverse systems, held at the National Science Seminar Complex, Indian Institute of Science, Bangalore 560012, India, December 13-15, 2010; Abstract number G009, printed in the abstract book page 157.
  • Gope R.  Presented an invited guest lecture entitled “Cancer genetics and chromosomal abnormalities” on the 17 March, 2011, at Acharya’s Bangalore B-School (ABBS), # 3 Lingadheeranahalli, Off Magadi Road, Bangalore 560091.
  • Gope R.  Presented an invited lecture entitled “Modulation of gene expression as a strategy to manage cognitive deficits” at the 1st National Conference on Neuropsychology & Cognitive Neurosciences”, held in NIMHANS, Bangalore on 24-27 November, 2011, Abstract number II.2, printed on page 9-10.
  • Gope R.  Presented an invited special lecture entitled “Chromosomal alterations in cancer” at the Center for Applied Genetics, Jnana Bharathi Campus, Bangalore University, Bangalore 560056 on 28 November, 2011.
  • Gope R.  Attended as a Special Invitee and gave an invited special lecture entitled “Gene therapy for brain tumors” on 24 January, 2012, at the Two Day National Seminar on “Current Trends in the development of Gene Therapy and Toxicotherapy in the Treatment of Cancer”.  The conference was held on 24 to 25 January, 2012,  sponsored by All India Council for Technical Education (AICTE), organized by Dayananda Sagar College, at the CD Sagar Center for Life Sciences, Dayananda Sagar College of Pharmacy, Shavige Malleshwara Hills, Kumaraswamy Layout, Bangalore 560078.
  • Gope R.  Attended as a guest invitee and delivered a special lecture entitled “Chromosomal aberrations in malignant neoplastic diseases with special reference to human brain tumors” on 25 January, 2012 at the “XIth All India Conference on Cytology and Cytogenetics”, conducted by the Society of Cytologists and Geneticists, India, and Bangalore University.  The conference was held on 23 to 25 January, 2012, organized by the Department of Molecular Biology, Bangalore University, Bangalore 560056.
  • Gope R.   Presented an invited guest lecture  entitled “Chromosomal aberrations in cancer” on the 6 March 2012, in the  “UGC Refresher Course in Life Sciences”.   The refresher course entitled “Recent trends in cytogenetics, molecular techniques and bioinformatics” was conducted for the benefit of college teachers and it was organized by Bangalore University, Jnana Bharathi Campus, Bangalore 560056.
  • Gope R.  Attended the Cluster Seminar entitled “Biology to New Biology: The Paradigm Shift” organized on 10 to 12 April, 2012, by the “School of Biological Sciences”, Central University of Kerala, Padennakad, Nileshwar, Kasaragod, Kerala and presented an invited lecture on 11 April, 2012, entitled “Genetic changes in human intracranial tumors”.
  • Gope R.  Presented an invited guest lecture entitled “Human Genome Project (HGP); Ethical, Legal and Social Issues (ELSI) – Eugenics, Euthenics, Euphenics” in the “CNE workshop on genetics, Incorporating genetic perspective into quality nursing practice” on 4 October, 2012.  The workshop was organized by T. John College of Nursing, Gottigere, Bannerghatta Road, Bangalore-560083.
  • Gope R.  Presented an invited lecture entitled, “Post translational modifications of proteins and their importance in drug development with special reference to human intracranial tumors” on Friday, 27 September 2013.  This international conference was entitled “Genomics and Proteomics Research” and was organized by SELECTBIO at Sheraton Bangalore, Brigade Gateway, Bangalore 560 055, on 27 and 28 September, 2013.
  • Gope R.  Presented an invited lecture entitled “RNAi and cancer research” in the DBT sponsored workshop on “RNAi technology and its application” held at Maharani’s Science College for women, Bangalore on 10 February, 2014.
  • Gope R.  As a resource person presented two invited lectures entitled “(a) Human brain tumors and (b) Effect of small molecules on the post translational modification of p53 protein in human VS tumors” at the “Refresher course for University and College teachers in the discipline of Biotechnology, Microbial Biotechnology and Bioinformatics” organized by the Academic Staff College of Bharathiar University, Coimbatore 641046, on 11 November, 2014.
  • Gope R.  Presented an invited lecture on 16 April 2015, entitled “Post translational      modifications in human cancer” at the Bangalore University Golden Jubilee Lecture Series (15-16    April, 2015).  The theme of the lecture series was “Biology in the Genomic Era” and it was held at the Jnana Jyothi Auditorium, Central College Campus, Bangalore University, Bangalore 560 001.
  • Gope R.  Attended the 3rd International Conference on “Genomics and Proteomics Research” organized by SelectBio at Sheraton Grand Bangalore Hotel at Brigade Gateway,  26/1 Dr. Rajkumar Road, Rajajinagar-Malleshwaram, , Bangalore 560 055, Karnataka, India on 28 and 29 May, 2015.  I also chaired two sessions in this conference (a) Session 2: Engineering Genome for Clinical Applications on 28 May 2015 and (b) Session 5: Current Approaches in Genomics and Proteomics Research on 29 May 2015.
  • Gope R.  Presented an invited lecture on 12 February, 2016, entitled “Dysregulated gene expression through post-translational modifications in human brain tumors” in the “Science Academie’s Lecture Workshop” on “Recent Trends in Cellular Mechanisms and Gene Expression” held in Xavier Hall, P.G. Center, St Joseph’s College (Autonomous), #46 Langford Road, Bangalore 560027.
  • Gope R.  Presented an invited lecture on 18 February, 2016, entitled “CRISPRCas9 system for targeted gene editing: a revolutionary tool in molecular biology” in the “National seminar on frontiers in biotechnology-NSFB-2016” held in Bharathiar University, Coimbatore 641 046, Tamil Nadu, on February 18-19, 2016.
Neurochemistry
  • Establishment of high-throughput mass spectrometry-based screening for lysosomal storage disorders using dried blood spots. Investigators: Dr. Rita Christopher,  Dr. Nagaraja D(Funding by DBT New Delhi)
  • Proteomic analysis of neurological stroke. Investigators: Dr. Rita Christopher, Dr. Nagaraja D, Dr. Yasha TC, Dr. Akilesh Pandey(Funding by DBT, New Delhi)
  • Vitamin D receptor gene variants and vascular risk: Study in ischemic stroke. Investigators:Dr. Rita Christopher, Dr. Nagaraja D, (Funding by ICMR, New Delhi)
  • Vitamin D status and vascular cognitive impairment in the elderly.Investigators: Dr. Rita Christopher, Dr.Chandra SR(Funding  by ICMR, New Delhi) 
  • Protective role of Withania somnifera against scopolamine induced memory impairment in Alzheimeric rats. Investigators:Dr. Visweswari G, Dr. Rita Christopher(Funding by DST)
  • A study of neuroprotective aspects of Klotho biology.Investigators: Dr. Vijaya Majumdar, Dr. Rita Christopher (Funding by DBT) 
  • Pharmacogenetics of oral anticoagulation therapy in patients with cardiac valve replacement. Investigators: Dr. Kalpana SR, Dr. Rita Christopher, Dr. Manjunath, (Funding by ICMR) 
  • Conformation dependent antibodies as therapeutic strategies for protein misfolding disorders. Investigator: Dr. Sarada Subramanian(Funding by DST, New Delhi)
  • Tau-focused immunotherapeutic approaches to Alzheimer’s disease. Investigator:   Dr. Sarada Subramanian (Funding by CSIR, New Delhi)
  • Biochemical and histological analysis of traumatic brain injury in neurotrauma patients.Investigators: Dr. Srinivas Bharath MM, Dr. Nupur  Pruthi, Dr. Shankar SK, Dr. Anita Mahadevan (Funding by ICMR)
  • Nanoassisted C60-pyrimidine derivatives: Their synthesis, characterization, neuroprotective and antiviral activities.Investigators: Dr. Srinivas Bharath MM, Dr. Devashish Sengupta, Assam University, Dr. Shaheed Jameel, ICGEB, New Delhi(Funding DBT, New Delhi)
  • Analysis of the epigenetic regulation of red/ox mechanisms in neurotoxic models of Parkinson’s disease: Role of chromatin modifications. Investigators: Dr. Mythri R, Dr. Srinivas Bharath MM(Funding by DST, New Delhi)
  • Role of Glutamate excitotoxicity and cytokines in invasion of glioblastoma. Investigators: Dr. Nandakumar DN, Dr. Sampath S, Dr. Vani Santosh(Funding by DBT, New Delhi)
  • Genetic and biochemical profiling of patients with glutaric aciduria type I.Investigator: Dr. Kruthika Vinod  TP(Funding by DST, New Delhi)
Neuromicrobiology
  • Whole genome sequencing analysis of Mycobacterium tuberculosis clinical isolates from extra pulmonary tuberculosis patients.Investigators: Dr. R Ravikumar,Dr. PSatishchandra, Dr. Keshava Prasad, Dr. Akhilesh Pandey (Funding by DBT)
  • Genomic and proteomic analysis of chronic meningitis. Investigators: Dr. RRavikumar (Funding by DBT)
  • Etiopathogenesis of chronic meningitis: Biochemical analysis and Molecular characterization of M. tuberculosis and C. neoformans in CSF of patients.Investigators: Dr. RRavikumar (Funding by ICMR)
  • Phenotypic identification and molecular characterization of blandm-1gene in multidrug resistant Gram negative bacilli isolated from clinical and environmental samples in a tertiary neurocare centre. Investigator:Dr. RRavikumar
  • Development of novel antimicrobial agents to overcome microbialresistance. Investigator: Dr. RRavikumar (Collaboration with JNCASR, Bangalore)
  • Identification of mycobacterium tuberculosis antigens of diagnostic potential in body fluids using high resolution mass spectrometry.Investigator: Dr. RRavikumar (Collaborative project with IOB, Bangalore and SDS TRC &Rajiv Gandhi Institute of Chest Diseases)
  • Proteomic analysis of chronic and acute meningitis using mass spectrometry-based approach.Investigators:  Dr. RRavikumar (Collaborative project with IOB, Bangalore)
  • Comparison between SACETT and SETT on the incidence of VAP in Neuro ICU. Investigators: Dr. SriGanesh, Dr. R Ravikumar, Dr.VeenaKumari HB
  • Confirmation and characterization of HA-MRSA and CA-MRSA. Investigators:   Dr.VeenaKumari HB, Dr. Nagarathna S (Funding by ICMR) 
  • Neuroleptospirosis-study of microbiological and clinical aspects-viral meningitis, Is it neuroleptospirosis? Investigators: Dr. Nagarathna S, Dr.VeenaKumari HB (Funding by ICMR)
  • Neurobrucellosis-microbiological and clinical evaluation.Investigators: Dr. Nagarathna S, Dr. Veena Kumari HB (Funding by ICMR)
Neurophysiology
  •  Glial responses in sporadic amyotrophic lateral sclerosis.Investigators: Dr. TR Raju, Dr. Phalguni Anand Alladi, Dr. Sathyaprabha TN, Dr. Nalini A, Mr. Dinesh Dhull (Funding by DBT)
  • Isolation and characterization of toxic factor(s) present in the CSF of amyotrophic lateral sclerosis patients. Investitagors: Dr. T R Raju, Dr. Nalini A,Dr. Sathyaprabha TN, Dr. Phalguni Anand Alladi, Dr. MM Srinivas Bharath, Dr. Aparna Sharma (Funding by DBT)
  • Isolation and characterization of toxic factor(s)present in CSF of patients suffering from Amyotrophic Lateral Sclerosis. Ms.Anu Mary Varghese. Guides: Dr. TR Raju, Dr. MMSrinivas Bharath,  Dr. Nalini A(Funding by CSIR Senior Research Fellow) 
  • A Study on the profiles of neurotrophic factor in the rat spinal motor neurons following exposure to cerebrospinal fluid from patients with sporadic Amyotrophic Lateral Sclerosis. Investigators: Dr. TR Raju, Dr. Sathyaprabha TN, Dr. Nalini A, Dr.Sumitha (Funding by ICMR) 
  • Effect of ALS-CSF on the expression of Neurofilament subunits in NSC-34 cells. Investigators: Dr. TR Raju, Dr. Sathyaprabha TN, Dr. Nalini A,Dr. Phalguni Anand Alladi, Dr. Vijayalakshmi K(Funding by NIMHANS)
  • Neural correlates of well-being associated with mindfulness meditation: A neuropsychophysiological and neuroimaging study. Investigators: Dr. Bindu M Kutty, Dr. John P John, Dr. Seema Mahrothra, Dr. Nirmala M (SRF), Dr. Jyothi K (JRF) (Funding by DST-CSI) 
  • Efficacy of Behavioral strategies of Enriched Environment and Physical Exercise with Dietary supplements on establishing a sustained functional recovery in Ventral SubicularLesioned rats. Investigators: Dr. Bindu M Kutty, Dr. Laxmi T Rao, Dr. Preethi Hegde (RA), Mr. Vijay Kumar K (SRF) (Funding by DBT)
  • Evaluation of EEG dynamics and sleep in Long term vs Short term practitioners of vipassana meditation.  Investigators:  Dr. Bindu M Kutty, Dr. S. Sulekha, Dr. TR Raju  (Funding by ICMR) 
  • Role of amygdala in the modulation of hippocampal and prefrontal cortical functions in stress: Implications for the treatment of affective disorders.Investigators: Dr. BS Shankaranarayana Rao, Dr. TR Raju(Funding by DBT)
  • Cellular and molecular basis of endogenous depression induced cognitive deficits. Investigators: Dr. BS Shankaranarayana Rao, Dr. TR Raju (Funding by DBT)
  • Evaluation of antiepileptic activity of medicinal plants in animal models of epilepsy. Investigator: Dr. BSShankaranarayana Rao (Funding by  DST) 
  • Effect of celestrus paniculatus on cognitive deficits in chronically stressed rats: A behavioral,neurochemical,structural and electrophysiological approach.Investigator:  Dr. BS Shankaranarayana Rao(Funding by DST)
  • Cellular and molecular basis of epilepsy-induced cognitive deficits. Investigator: Dr. B.S. Shankaranarayana Rao (Funding by DBT)
  • Cellular, molecular and electrophysiological basis of depression-induced cognitive deficits.Investigator: Dr. BS Shankaranarayana Rao, Dr. Mahati Krishna, (Funding by CSIR) 
  • Maternal separation anxiety and fear learning/memory: Effects on sleep architecture in adulthood.Investigators: Dr. Laxmi T Rao, Dr. Bindu M Kutty, Dr. Shravanthy (Funding by CSIR )
  • A multimodal approach to evaluate the efficacy of enriched environment in ameliorating early maternal separation induced changes in brain function: A morphological, biochemical and behavioural study in rats.Investigators:  Dr. Laxmi T Rao, Dr. Bindhu OS, Jain University, Bangalore(Funding CSIR and ICMR) 
  • Evaluation of age-related synaptic changes in human substantia nigra pars compacta. Investigator: Dr. TR Raju (Funding by ICMR)
  • Evaluation of developmental apoptosis and nigral neuronal response in two mice strains with differential sensitivity to 1-methyl-4-phenyl-1, 2,3,6- tetrahydropyridine (MPTP) and their crossbreds. Investigator:Dr. TR Raju(Fundingby Science and Engineering Research Board, DST)
Neurovirology
  • Inflammation in Japanese encephalitis: role of IL2.  Investigators:  Dr. Tom Solomon, Dr. V. Ravi, Dr.  Anita Desai (Funding by MRC, UK)
  • Immunopathogenesis of rabies: experimental studies in mice. Investigators: Dr. SN Madhusudana, Dr. Abhay Chowdhury (Funding by DBT)
  • To investigate the antiviral property of an herbal extract against rabies virus by in vitro and in vivo studies. Investigators: Dr. S.N.Madhusudana,  Dr. Anita Desai, (Funding  by  ICMR)
  • To study the neutralizing efficacy of 5 human rabies monoclonal antibodies produced by Celltrion, Korea.  Investigators: Dr. SN Madhusudana, Dr. Reeta Mani, (Funding by Celltrion, Korea) 
  • Th1 and Th2 Immune responses to different schedules of rabies vaccination. Investigators: Dr. SN Madhusudana, Dr. Manjunath (Non-funded)
  • Understanding the biology of Chikungunya virus infection in permissive cell lines and mosquitoe vectors.  Investigators:   Dr. Anita Desai, Dr. Brij Kishor Tyagi, CRME-ICMR, Madurai, Dr SN Madhusudana (Funding by DBT)
  • Strenthening surveillance for Japanese encephalits in India. Investigators:  Dr. V. Ravi, Dr.Anita Desai, Dr. Reetamani (Funding  byCentre for Disease Control, USA)
  • Immune signatures in Dengue virus infection.  Investigators:  Dr. V. Ravi, Dr. Anita Desai and In collaboration with University of Yale (Funding by Indo USA Vaccine Action Program Grant) 
  • Immunological aspects of Chikungunya virus infection with special reference to pathogenesis. Mr. R Vijayalakshmi. Guides: Dr. Ravi Vasanthapuram, Dr. Anita Desai  (Non-funded) 
  • A comparative study of innate and cell-mediated immune responses in human immunodeficiency virus infected individuals with and without neurotuberculosis.  Ms. Deepashri Rao. Guides:  Dr. Anita Desai, Dr. V. Ravi, Dr. P. Satish Chandra (Non-funded) 
  • Study on molecular aspects of the pandemic Influenza A 2009 (H1N1) virus with special reference to host immune factors. Investigators: Ms. Maria Thomas. Guides: Dr. V. Ravi, Dr. Anita Desai (Non-funded) 
  • The molecular mechanisms involved in chikungunya virus – Host cell interaction.  Mr. Ayushman Ghosh. Guides: Dr.  Anita Desai, Dr. SN Madhusudana, Dr. N Gayathri  (Non-funded) 
Psychopharmacology
  • Electroconvulsive seizure – induced neuroplasticity changes in the rat brain. Investigators:   Dr. Chittaranjan Andrade, Dr Sumantra Chatarji, Dr. B.K. Chandrasekhar Sagar, Ravi Prabhakar Hegde (Funding by DBT and ICMR)
  • Study of visuospatial memory in an animal model of ECT.  Investigators:  Dr. Chittaranjan Andrade (Non-funded) 
  • Meta-analysis of ar/modafinil in schizophrenia.  Investigator:  Dr. Chittaranjan Andrade (Non-funded)
  • Efficacy of herbal cognition enhancers in learning and ECS-induced amnesia.  Investigator: Dr. Chittaranjan Andrade (Non-funded) 
  • Investigation of ECS-induced oxidative stress and retrograde amnesia.  Investigator: Dr. Chittaranjan Andrade (Non-funded)
  • A study to evaluate the effectiveness of an educational module on knowledge about, experiences with, and attitudes towards antidepressant drugs in antidepressant-naïve depressed patients.   Investigators:  Dr. Chittaranjan Andrade  (Non-funded)
  • Alteration of heart rate variability and cardiac electrophysiological variables in a rodent model of brain stimulation. Mr. Nagendra Madan Singh. Guides: Dr. Chittaranjan Andrade, Dr Jagadisha T (Funding by ICMR)
Instituitional Research
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