Centre for Brain and Mind

Centre for Brain and Mind

About Us

The Centre for Brain and Mind is a collaborative, premier research centre focused on supporting research on five mental disorders — schizophrenia, bipolar disorder, addiction, obsessive-compulsive disorder and dementia. With a partnership between the National Institute of Mental Health and Neurosciences (NIMHANS) and the National Centre for Biological Sciences (NCBS), the centre employs several tools & techniques to understand the complexities of brain and mind conditions. 
For More Details – https://www.cbmnimhans.org/

Recent Publications

  1.  A rare case of Niemann Pick Disease with a novel variant in the NPC2 gene presenting with neuropsychiatric manifestations in middle age. Agarwal, A.; Praveen, A. P.; Singhai, K.; Ashitha, S.; Purushottam, M.; Jain, S.; and Moirangthem, S. Asian Journal of Psychiatry, 97: 104089. July 2024.
  2.  An evolutionary perspective on complex neuropsychiatric disease. McClellan, J. M.; Zoghbi, A. W.; Buxbaum, J. D.; Cappi, C.; Crowley, J. J.; Flint, J.; Grice, D. E.; Gulsuner, S.; Iyegbe, C.; Jain, S.; Kuo, P.; Lattig, M. C.; Passos-Bueno, M. R.; Purushottam, M.; Stein, D. J.; Sunshine, A. B.; Susser, E. S.; Walsh, C. A.; Wootton, O.; and King, M. Neuron, 112(1): 7–24. January 2024. Place: United States
  3.  Altered neuroepithelial morphogenesis and migration defects in iPSC-derived cerebral organoids and 2D neural stem cells in familial bipolar disorder. Phalnikar, K.; Srividya, M; Mythri, S V; Vasavi, N S; Ganguly, A.; Kumar, A.; S, P.; Kalia, K.; Mishra, S. S; Dhanya, S. K.; Paul, P.; Holla, B.; Ganesh, S.; Reddy, P. C.; Sud, R.; Viswanath, B.; and Muralidharan, B. Oxford Open Neuroscience, 3: kvae007. February 2024.
  4.  Deep Intronic FGF14 GAA Repeat Expansion in Late-Onset Cerebellar Ataxia. Pellerin, D.; Danzi, M. C.; Wilke, C.; Renaud, M.; Fazal, S.; Dicaire, M.; Scriba, C. K.; Ashton, C.; Yanick, C.; Beijer, D.; Rebelo, A.; Rocca, C.; Jaunmuktane, Z.; Sonnen, J. A.; Lariviere, R.; Genis, D.; Molina Porcel, L.; Choquet, K.; Sakalla, R.; Provost, S.; Robertson, R.; Allard-Chamard, X.; Tetreault, M.; Reiling, S. J.; Nagy, S.; Nishadham, V.; Purushottam, M.; Vengalil, S.; Bardhan, M.; Nalini, A.; Chen, Z.; Mathieu, J.; Massie, R.; Chalk, C. H.; Lafontaine, A.; Evoy, F.; Rioux, M.; Ragoussis, J.; Boycott, K. M.; Dube, M.; Duquette, A.; Houlden, H.; Ravenscroft, G.; Laing, N. G.; Lamont, P. J.; Saporta, M. A.; Schule, R.; Schols, L.; La Piana, R.; Synofzik, M.; Zuchner, S.; and Brais, B. The New England journal of medicine, 388(2): 128–141. January 2023. Place: United States
  5.  Metagenomic data reveals microbiome characteristics of culture-negative brain abscess samples. John, D. V.; and Purushottam, M. Data in brief, 46: 108893. February 2023. Place: Netherlands
  6.  Growth trajectories for executive and social cognitive abilities in an Indian population sample: Impact of demographic and psychosocial determinants. Sharma, E.; Ravi, G. S.; Kumar, K.; Thennarasu, K.; Heron, J.; Hickman, M.; Vaidya, N.; Holla, B.; Rangaswamy, M.; Mehta, U. M.; Krishna, M.; Chakrabarti, A.; Basu, D.; Nanjayya, S. B.; Singh, R. L.; Lourembam, R.; Kumaran, K.; Kuriyan, R.; Kurpad, S. S.; Kartik, K.; Kalyanram, K.; Desrivieres, S.; Barker, G.; Orfanos, D. P.; Toledano, M.; Purushottam, M.; Bharath, R. D.; Murthy, P.; Jain, S.; Schumann, G.; and Benegal, V. Asian journal of psychiatry, 82: 103475. April 2023. Place: Netherlands
  7.  Delusions, Hallucinations, and Cognitive Decline in Middle Age: A Case of Dementia, GIGYF2 Gene Mutation, and 22q11 Duplication. Nadella, R. K.; Pulaparambil, V.; Vemula, A.; P, S. L.; Saini, J.; Nagaraj, C.; Purushottam, M.; Viswanath, B.; Sullivan, P. F.; and Jain, S. Indian journal of psychological medicine, 45(3): 317–319. May 2023. Place: United States
  8.  Risk clustering and psychopathology from a multi-center cohort of Indian children, adolescents, and young adults. Basu, D.; Ghosh, A.; Naskar, C.; Balachander, S.; Fernandes, G.; Vaidya, N.; Kumaran, K.; Krishna, M.; Barker, G. J.; Sharma, E.; Murthy, P.; Holla, B.; Jain, S.; Orfanos, D. P.; Kalyanram, K.; Purushottam, M.; Bharath, R. D.; Varghese, M.; Thennarasu, K.; Chakrabarti, A.; Singh, R. L.; Singh, R. L.; Nanjayya, S. B.; Ahuja, C. K.; Kartik, K.; Krishnaveni, G.; Kuriyan, R.; Kurpad, S. S.; Desrivieres, S.; Iyengar, U.; Zhang, Y.; Hickman, M.; Spiers, A.; Toledano, M.; Schumann, G.; and Benegal, V. Development and psychopathology, 35(2): 800–808. May 2023. Place: United States
  9.  Molecular genetics of neuropsychiatric illness: some musings. Janardhanan, M.; Sen, S.; Shankarappa, B.; and Purushottam, M. Frontiers in genetics, 14: 1203017. 2023. Place: Switzerland
  10.  Federated Analysis in COINSTAC Reveals Functional Network Connectivity and Spectral Links to Smoking and Alcohol Consumption in Nearly 2,000 Adolescent Brains. Gazula, H.; Rootes-Murdy, K.; Holla, B.; Basodi, S.; Zhang, Z.; Verner, E.; Kelly, R.; Murthy, P.; Chakrabarti, A.; Basu, D.; Bhagyalakshmi Nanjayya, S.; Lenin Singh, R.; Lourembam Singh, R.; Kalyanram, K.; Kartik, K.; Kalyanaraman, K.; Ghattu, K.; Kuriyan, R.; Kurpad, S. S.; Barker, G. J.; Bharath, R. D.; Desrivieres, S.; Purushottam, M.; Orfanos, D. P.; Sharma, E.; Hickman, M.; Toledano, M.; Vaidya, N.; Banaschewski, T.; Bokde, A. L. W.; Flor, H.; Grigis, A.; Garavan, H.; Gowland, P.; Heinz, A.; Bruhl, R.; Martinot, J.; Paillere Martinot, M.; Artiges, E.; Nees, F.; Paus, T.; Poustka, L.; Frohner, J. H.; Robinson, L.; Smolka, M. N.; Walter, H.; Winterer, J.; Whelan, R.; Turner, J. A.; Sarwate, A. D.; Plis, S. M.; Benegal, V.; Schumann, G.; and Calhoun, V. D. Neuroinformatics, 21(2): 287–301. April 2023. Place: United States
  11.  Neurocognitive Analysis of Low-level Arsenic Exposure and Executive Function Mediated by Brain Anomalies Among Children, Adolescents, and Young Adults in India. Vaidya, N.; Holla, B.; Heron, J.; Sharma, E.; Zhang, Y.; Fernandes, G.; Iyengar, U.; Spiers, A.; Yadav, A.; Das, S.; Roy, S.; Ahuja, C. K.; Barker, G. J.; Basu, D.; Bharath, R. D.; Hickman, M.; Jain, S.; Kalyanram, K.; Kartik, K.; Krishna, M.; Krishnaveni, G.; Kumaran, K.; Kuriyan, R.; Murthy, P.; Papadopoulos Orfanos, D.; Purushottam, M.; Kurpad, S. S.; Singh, L.; Singh, R.; Subodh, B. N.; Toledano, M.; Walter, H.; Desrivieres, S.; Chakrabarti, A.; Benegal, V.; and Schumann, G. JAMA network open, 6(5): e2312810. May 2023. Place: United States
  12.  Hypomethylation of Long Interspersed Nucleotide Elements and Aldehyde Dehydrogenase in Patients of Alcohol Use Disorder with Cirrhosis. Shankarappa, B.; Mahadevan, J.; Murthy, P.; Purushottam, M.; Viswanath, B.; Jain, S.; Devarbhavi, H.; and Mysore Visweswariah, A. DNA and cell biology, 42(7): 364–371. July 2023. Place: United States
  13.  Non-synaptic mechanisms of antipsychotics may be key to their actions. Sud, R.; Banerjee, A.; Viswanath, B.; Purushottam, M.; and Jain, S. Schizophrenia research, 261: 128–129. November 2023. Place: Netherlands\