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Faculty

Dr. Mathivanan Jothi

 

 

Dr. Mathivanan Jothi

 

 

Designation

 

    Assistant Professor

 

Associated with NIMHANS as faculty since (Month and Year)

    January, 2017

 

 

Employment History

 

Aug 2014 to Jan 2017     UGC-Assistant professor, Bharathiar University, Coimbatore, India

Mar 2013 to July 2014     DTI-IMPORT Fellow, San Raffaele Scientific Institute, Milan, Italy

Dec 2012 to Feb 2013       Post-Doctoral Associate, Roswell Park Cancer Institute, Buffalo, NY USA

Apr 2008 to Dec 2012       Research Affiliate (Post doc), Roswell Park Cancer Institute, Buffalo, NY USA

Dec 2007 to Mar 2008       Postdoctoral Fellow, Cleveland Clinic, Cleveland, OH, USA

Educational Qualifications

      M.Sc., Ph.D

Awards, Fellowships and Recognitions, Memberships

 

    Awards:

1. Dulbecco Telethon Institute International Mobility for   Postdoctoral Research Training (DTI-IMPORT) fellowship, Dulbecco Telethon Institute, Italy

2. Senior Research Fellow, University Grants Commission, India (UGC-SRF)

3. Junior Research Fellow and eligible for lectureship, University Grants Commission, India (UGC-JRF/LS)

4. Junior Research Fellow, Indian Council of Medical Research, India (ICMR-JRF)

International Presentation Award:

1. Best poster award with travel grant (First price)- Presented at Scientific Retreat, Cell Stress and Biophysical Therapies Program & Cell Stress Biology, May 6-7, 2012 Holiday Inn, Grand Island, NY 14072

2. Best poster award (First Place)- Presented at 2010 Postdoc Research Symposium, June 8th, 2010 Center for Tomorrow, North Campus, University at Buffalo, Buffalo, NY 14201

Membership in societies:

1. Active member-American Association of Cancer Research (AACR)

2. Advisory Board/council member – FOCUS ON RHABDO-a community focused on finding the cure for rhabdomyosarcoma 

Contact Information

 Phone: +91 80 2699 5125/5124 Fax: +91 80 2656 4830

 Mobile: +91 8220455752

 Email: mjothi@nimhans.ac.in        

             mathivanan.jothi@gmail.com   

 Website: http://lmtnimhans.weebly.com

Areas of Research Interest

 

   Cellular differentiation; Transcription factors; Tissue  regeneration; Epigenetics; Pediatric diseases; Cancer biology.

 

Selected publication

1. Chatterjee B, Wolff DW, Jothi M, Mal M, Mal AK. p38α MAPK disables KMT1A-mediated repression of myogenic differentiation program. Skelet Muscle. 2016 Aug 22;6:28. doi: 10.1186/s13395-016-0100-z. eCollection 2016. PubMed PMID: 27551368; PubMed Central PMCID: PMC4993004.

2. Mitra R, Keshava R, Jothi M, Vikas V, Indira Devi B, and Gope R. Bay 61-3606, CDKi and sodium butyrate treatments modulate p53 protein level and its site-specific phosphorylation in human vestibular schwannomas in vitro. Journal of Cancer Research 2014; 2014: 249354 doi: 10.1155/2014/249354

3. Jothi EA, Sundaram M, Namasivayam J, Jothi M. A rare presentation of retiform hemangioendothelioma in the external auditory canal. Case Rep Otolaryngol. 2014; 2014: 715035. doi: 10.1155/2014/715035. Epub 2014 Jul 13. PubMed PMID: 25184066; PubMed Central PMCID: PMC4122065.

4. Neguembor MV, Jothi M, Gabellini D. Long noncoding RNAs, emerging players in muscle differentiation and disease. Skelet Muscle. 2014 Mar 31;4(1):8. doi: 10.1186/2044-5040-4-8. PubMed PMID: 24685002; PubMed Central PMCID: PMC3973619.

5. Jothi M, Mal M, Keller C, Mal AK. Small molecule inhibition of PAX3-FOXO1 through AKT activation suppresses malignant phenotypes of alveolar rhabdomyosarcoma. Mol Cancer Ther. 12: 2663-2674, 2013.

6. Jothi M, Mal AK. Too much AKT turns PAX3-FKHR dead: A prospect of novel therapeutic strategy for alveolar rhabdomyosarcoma. Oncotarget. 3(10):1064-5, 2012.

7. Jothi M, Nishijo K, Keller C and Mal A. AKT and PAX3-FKHR cooperation enforces myogenic differentiation blockade in alveolar rhabdomyosarcoma cell. Cell Cycle 11(5): 895-908, 2012

8. Lee MH, Jothi M, Gudkov AV, Mal AK. Histone Methyltransferase KMT1A Restrains Entry of Alveolar Rhabdomyosarcoma Cells into a Myogenic Differentiated State. Cancer Res 71: 3921-3931, 2011.